ZyMōt™ Multi 850 Sperm Separation Devices (Box of 10)

ZyMōt™ Fertility from DxNow, Inc.

2 reviews   |  
Product image 1ZyMōt™ Multi 850 Sperm Separation Devices (Box of 10) - IVF Store
Product image 2ZyMōt™ Multi 850 Sperm Separation Devices (Box of 10) - IVF Store
Product image 3ZyMōt™ Multi 850 Sperm Separation Devices (Box of 10) - IVF Store
Product image 4ZyMōt™ Multi 850 Sperm Separation Devices (Box of 10) - IVF Store
Product image 5ZyMōt™ Multi 850 Sperm Separation Devices (Box of 10) - IVF Store
Product image 6ZyMōt™ Multi 850µl Sperm Separation Device Packaging
Product image 7ZyMōt™ Multi 850 Sperm Separation Devices (Box of 10) - IVF Store

Regular price $1,595.00 [Price Match]

SKU: ZMH0850



This product is restricted to sale for physicians and IVF clinics only.

ZyMōt™ Multi 850µl


In 5+ decades of reproductive medicine, technological innovations have changed the way patients achieve their dreams. Despite this progress, sperm preparation has not evolved: labs still centrifuge sperm. Until now.

The ZyMōt Multi (850µL) Sperm Separation Device prepares motile sperm from semen for use in intrauterine insemination (IUI) and intracytoplasmic sperm injection (ICSI) procedures. The device accepts 850µL of sample input and yields 500µL output volume for downstream use.

ZyMōt devices separate sperm based on motility, without the need for any centrifugationClick here to learn more about how ZyMōt devices work

With about 5 minutes of total hands-on time per sample, every ZyMōt processed specimen represents a significant time savings over centrifugation-based methods. Simple to adopt and easy to use, ZyMōt devices improve training and standardization, helping your practice increase its productivity. No special media is required. Fewer handling steps (a shorter chain of custody) translates into less risk for your lab, and more confidence for your patients. Learn more about how ZyMōt Sperm Separation Devices improve workflow and productivity.

The ZyMōt Multi (850µL) device can be used with the following sample types: 

  • “Normal”
  • Low count
  • Low motility (Note: Some motility is required)
  • Viscous
  • Low volume
  • A combination of the above properties
  • Frozen samples

Read more about the clinical performance of ZyMōt devices and see the publications featuring ZyMōt data.

Whether for ICSI or IUI use, there is no need for any centrifugation of the sample, either before or after device usage. Processing sperm with ZyMōt devices gives you more confidence and gives your patients more peace of mind.

Try it yourself and see the ZyMōt difference.

ZyMōt devices are Made in the USA.


ZyMōt devices separate sperm based on motility.

 The ZyMōt Multi (850μL) Sperm Separation Device has an inlet port, an outlet port and a membrane filter. 850uL of raw semen is injected into the inlet port. The sample travels into the lower portion of the device, underneath a membrane that has 8 micron pores. Fertilization media is placed on top of the membrane. During incubation, the healthiest, most progressively motile sperm migrate through the pores into the fresh media above. They leave behind the less motile, morphologically abnormal sperm. After incubation, what is collected from above the membrane are the healthiest, most genomically competent sperm. ZyMōt separates the champions.


  • No centrifugation
  • Sperm separation based on motility/performance
  • Less than 5 minutes of active, hands-on time
  • Separates healthy, normal morphology sperm from the heterogeneous mix in a semen sample
  • Sperm ready for immediate downstream use in ICSI and IUI procedures
  • Fast, standardized training, with easy-to-understand instructions
  • No expensive equipment – only requires the use of syringes
  • FDA 510(k) clearance. (FDA approval documents)
  • Sterile, single-use devices
  • Made in the USA
  • 2-year expiration dating


ZyMōt enriches a sample for the healthiest sperm: Lower DNA fragmentation and oxidative stress

“Overall, the quality of the sperm obtained post-processing was improved by the use of the [ZyMōt] separation device” – Broussard, 2019

Reference: Broussard A. et al. Fertility and Sterility, Volume 111, Issue 4, e15.

ZyMōt enriches a sample for the healthiest sperm: Progressively motile, morphologically normal

Outcomes matter: ZyMōt improved sperm health and ICSI pregnancies

A 2019 publication from Weill-Cornell Medicine:

  • A “remarkable reduction” of DNA fragmentation. 
  • Sperm with “higher genomic competence”, improved motility and morphology.
  • Improved euploid rate and the ability to establish healthy pregnancies.

Reference: Parrella, A., et al. J Assist Reprod Genet (2019). doi: 10.1007/s10815-019-01543-5

ZyMōt devices aren’t just advancing patient care for ICSI procedures. Historically, IUI success rates have been low, and patients with male-factor issues have additional challenges that impede success. ZyMōt devices have been shown to improve the success rates for IUI procedures.

Outcomes matter: Improved pregnancy rates in a published study of 265 IUI patients

Reference: Gode, F. et al. Fertil Steril (2019). doi: 10.1016/j.fertnstert.2019.06.037

How to Use the ZyMōt Multi (850µL) Sperm Separation Device


Mfr No. ZMH0850
ZyMōt Multi 850μl (Box of 10)


Customer Reviews
5.0 Based on 2 reviews
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  • support
  • Criag
  • place
  • surface tension
  • well
  • sperm wash overlay
  • ZyMot
  • ICSI
  • sperm
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Adrienne K.
United States United States
I recommend this product
Great company

Criag is so great he is always helpful and provides great support when needed. IVF Store is our go to place!

United States
Great Product

We've so far enjoyed the ease of use with the ZyMot slides and obtaining very, very clean highly motile sperm for ICSI. Our only issue initially was that it is not made clear that the sperm wash overlay must spill over in to the second small well, and it does not on it's own due to the surface tension, and so you have to start adding sperm wash there and then move over to the larger well.

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