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CEROS II Sperm Analysis System
The CEROS II is a highly accurate sperm analyzer that is a cost-effective alternative to our industry leading IVOS CASA system (Computer Assisted Sperm Analysis). Perform semen quality assessment for sperm count and concentration; motile categories like static, motile, progressive. View detailed kinematic values for each cell and the kinematic profiles for the entire population. For over 30 years, Hamilton Thorne has been helping IVF professionals and animal researchers obtain sperm analysis results for applications in multiple markets. Our CEROS II CASA system provides precise, objective, and repeatable results that you can trust.
- Unique color-coded illumination to optimize identification of the sperm head and tail
- Cost-effective and space-saving sperm analyzer with external phase contrast microscope included
- Additional software modules for DNA Fragmentation, Morphology
*availability of software modules various per application
Not for clinical diagnostic procedures in USA – for research purposes only
Performing semen analysis is essential for evaluating male factor infertility in IVF applications. Our CEROS II sperm analyzer provides an efficient method for performing semen assessment in the lab.
- Semen Analysis for counts, motility, progressive, concentration, volume
- Sperm Functional Tests
- DNA Fragmentation with SCD assay (Sperm Chromatin Dispersion Test)
- Sperm Morphology
Specifications
| CEROS II | Microscope: ZEISS Axio lab A5 |
|---|---|
| Objectives | Standard: 10x negative or positive phase, 20x brightfield, 100x brightfield |
| Image Type | Negative or Positive Phase Contrast Brightfield |
| Temperature Control | Minitherm stage warmer available as an accessory for temperature control. |
| Compatible Specimen Chambers | Type: 20 micron depth slide |
| Image Acquisition | Frame Rate: 60 Hz Frames: 1 – 60 Fields: 1 – 100 Field Selection: Manual |
| Power Requirements | Input voltage: 110-240 VAC Power: 250 watt (max) Line Frequency: 50/60 Hz |
Features & Benefits
The CEROS II sperm analyzer provides the same analysis software as the IVOS II at a cost-effective price point and space-saving footprint in your lab. It is ideal for lower volume throughput labs, and groups that maintain strict operating procedures surrounding equipment and higher skill set technicians. For high volume and high turn over labs with lower skill set requirements, the automated IVOS may be more ideal for your setting.
Spend less time on learning a new system with the CEROS II’s intuitive Windows-based software platform and standard illumination controls.
Software
The CEROS II sperm analyzer is powered by our user-friendly HT CASA software. Analyze immotile, motile, progressive, slow cell, and total concentration using WHO 4, 5, or 6 parameters.
Color-coded Parameters and Interactive Illumination Check
- Motile sperm identified by color-coded tracks and static sperm identified by red dot.
- Unique color-coded Illumination helps optimize identification of the sperm head and tail.
- Motility track overlay on playback image and results may be visible or turned off.
Analysis Results Updated in Real Time
- WHO Standards and Analysis Results are updated in real-time as each field is added.
- Captured fields with motility tracks are displayed in video thumbnail gallery.
- Selecting a field from thumbnail gallery displays summary counts and kinematics.
- Each track can be selected and zoomed to display detailed results.
- Results can be saved to the database.
Customized Reports
- Analysis results can be exported via ASCII file output.
- Display sperm analysis results with user-friendly drag and drop report designer.
- Unlimited number of customized reports including analysis images.
Replicate Analysis
- Perform replicate analysis following WHO guidelines between two different chambers
- Determine if the replicate samples are within acceptable difference by calculating the highest average of cells within the motile category.
- Perform calculations automatically within the software.
Internal Quality Control Modules
- Internal Quality Control (IQC) feature verifies microscope objective calibration daily.
- Using standardized quality materials of known concentrations, the IQC system tracks daily performance results before initiating patient samples.
- Determine if the replicate samples are within acceptable difference by calculating the highest average of cells within the motile category.
- Findings are automatically tested to the Westgard Rules integrated into the software to provide Pass/Fail results for analytical runs with QC material. Results are displayed in a Levey-Jennings chart.
Optional Software Modules
Morphology
The DIMENSIONS II Morphology software automatically classifies the morphology of fixed stained human sperm samples according to the Tygerberg strict criteria.
- Obtain objective, repeatable results when analyzing sperm for normal, sub-normal, or abnormal morphology.
- Display TZI (Teratozoospermia Index) results: The total number of defect points encountered during an analysis, divided by the number of Abnormal and Sub-normal cells.
- Classify sperm by morphological characteristics of the sperm head size and shape, acrosome, and tail.
- Compatible with Diff-Quick or Papanicolaou (PAP) stains.
DNA Fragmentation
The DNA Fragmentation Software evaluates the level of DNA integrity from sperm smears prepared with the Halosperm® G2 test kit from Halotech® DNA based on the Sperm Chromatin Dispersion (SCD) Test (Fernandez et al., J. Androl 24:59-66,2003; Fertil Steril 84:833-842,2005).
- Analyzes prepared sperm samples and measures the size of the halo (large halo, medium halo, small halo, or no halo).
- Displays the number and percentage of sperm showing a Large Halo, Medium Halo, Small Halo or No Halo
- Categorizes cells as normal, fragmented, or degraded.
- Results are shown per selected field and per selected cell.
