Its unique design allows an hermetic seal which is created by a tapered surface where the Cryolock body and cap fit in a perfect seal creating a closure system able to keep the tip isolated from liquid nitrogen ( LN2) once the Cryolock is submerged into the LN2.
While Cryolock is under LN2 the cap shrinks over the sealing area due to the low temperatures. While specimens are stored LN2 cannot recirculate inside the cap towards the tip or vice versa.
When Cryolock is used as a Semi-Closed System, the ONLY time specimens are in direct contact with LN2 is during capping step under LN2. In this case is recommended to use individual batches of LN2 for patients in order to reduce the risk of cross-contamination during cryopreservation procedures.
When Cryolock is used as a Closed System specimens are never in direct contact with LN2 thus avoiding the risk of cross-contamination during cryopreservation procedures and storage conditions.
Cryolock use instructions [pdf]
Cryolock is FDA 510(k) Cleared, CE Mark Approved and Health Canada Approved.